Titusville is a city in Brevard County, Florida, United States. The population was 40,670 at the 2000 census. As of 2008, the estimated population according to the U.S. Census Bureau was 44,756. It is the county seat of Brevard County. Called "Space City, USA," Titusville is a popular area situated near the Kennedy Space Center and Canaveral National Seashore. Titusville is a principal city of the Palm Bay–Melbourne–Titusville Metropolitan Statistical Area.